NTLA
Intellia Therapeutics, Inc. (NTLA) Economic Moat Analysis (2026)
Overall Score
Scale Market Position
NTLA remains a small-cap company with a market cap of about $1.66B, limiting scale advantages versus larger biotech peers.
Revenue per share is only $0.45 TTM, indicating a still-early commercial footprint.
Pricing Power Margin Structure
Gross margin is deeply negative at -46.5% TTM, showing the business is not yet generating product-level profitability.
Operating and net margins remain severely negative at -7.1% and -6.7% TTM, respectively, suggesting no durable pricing power yet.
Capital Efficiency Returns
Return on invested capital is -52.9% TTM and return on equity is -57.8% TTM, both indicating very weak capital efficiency.
Return on assets is -46.7% TTM, reinforcing that the company is still far from earning attractive economic returns.
Balance Sheet Financial Resilience
The current ratio of 6.65x and cash ratio of 1.34x indicate strong near-term liquidity.
Debt remains modest with debt-to-equity of 0.10x and debt-to-assets of 0.09x, reducing balance-sheet risk.
Intangible Assets Switching Costs
No material intangible asset base is visible, with intangibles-to-total-assets at 0.
There is no evidence in the current data of switching costs or other customer lock-in supporting a moat.
Network Effects Ecosystem
The available metrics and news do not indicate any network effects or ecosystem advantages.
NTLA appears to compete on scientific platform execution rather than on a self-reinforcing user network.
Regulatory Ip Scientific Moat
As a gene-editing company, NTLA likely benefits from patent and regulatory barriers that can protect platform know-how.
However, the current financials do not yet show that these protections are translating into durable economic profits.
Sources
- Company filings (10-K, 10-Q, investor presentations)
- Financial and market data providers
- Public news and industry information
🔒 Go Beyond This Framework
This is one of 10 institutional-grade frameworks Invetso runs on Intellia Therapeutics, Inc.. Unlock the complete analysis — SWOT, Economic Moat, Porter’s Five Forces, Management, PESTLE and the Invetso Quality Score.

